Comparing outcomes of patients with early active rheumatoid arthritis initially treated on an inpatient or outpatient basis: a posthoc analysis of the CORRA (CORRA) trial
Primary result · CDAI remissionResult — go to the resultOR for CDAI remission (multivariable model) 2.91 CI 1.37–6.14Authors' conclusion
In early active RA, initial inpatient treatment was associated with higher CDAI remission rates at weeks 8 and 12.
Study context
- Population
- Patients with early active rheumatoid arthritis (RA) in the CORRA trial of glucocorticoid (GC) bridging strategies, Germanyanalysed
- Participants
- 95 vs 280
- Comparison
- Initial inpatient vs outpatient treatment of early active RA
- Inpatientsn = 95
- Outpatientsn = 280reference
- Primary endpoint
- CDAI remission at weeks 4, 8 and 12
- Follow-up
- Weeks 4, 8 and 12
Methodological detailsnon-randomised comparison of initial treatment setting, multivariable model, No randomisation regarding the initial treatment strategy
- Non-randomised comparison of initial treatment setting
- Multivariable model
- No randomisation regarding the initial treatment strategy
Primary result
CDAI remission · week 12
OR for Clinical Disease Activity Index (CDAI) remission (multivariable model)
2.91
CI 1.37–6.14
P = 0.005
By group
Inpatientsvs Outpatients
OR for CDAI remission (multivariable model) 2.91 (CI 1.37–6.14); P = 0.005
As reported in the abstract
Further findings
| Outcome | Inpatients | Outpatients | OR for CDAI remission (multivariable model) (CI) | P value | |
|---|---|---|---|---|---|
| CDAI remission · week 8 | 24.7% | 14.9% | 2.43 (1.06–5.55) | P = 0.035 | |
| 0.20.5125OR for CDAI remission (multivariable model) (log scale) |
Original publication
Comparing outcomes of patients with early active rheumatoid arthritis initially treated on an inpatient or outpatient basis: a posthoc analysis of the CORRA trial. RMD Open. Published 22 October 2024. doi:10.
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