Vasculitis & polymyalgia rheumatica
Clinical value of diagnosing ischaemic stroke in patients with Takayasu's arteritis combining multiple arterial occlusion and high-grade enhancement
Authors' conclusion
A higher number of cervical artery occlusions and high-grade enhancement (grade ≥2) are independent risk factors for ischaemic stroke in patients with TAK.
Study context
- Population
- Patients with TAK who underwent vascular US and contrast-enhanced US on admission
- Participants
- 80 patients
- Outcome
- Ischaemic stroke and its independent US-related risk factors
Methodological detailsmultiple logistic regression, net reclassification and integrated discrimination improvement indices
- Multiple logistic regression
- Net reclassification and integrated discrimination improvement indices
Main finding
As reported in the abstract
Independent factors for ischaemic stroke (multivariate analysis)
Ischaemic stroke prevalence
22
27.5%
Number of occluded arteries, OR
2.01
p=0.005
High-grade enhancement (grade ≥2), OR
6.52
p=0.016
Revascularisation, OR
0.05
p=0.002
Observational data: associations, not effects.
Further findings
Infarction territory among patients with ischaemic stroke
- Anterior circulation infarction
- 14
- Posterior circulation infarction
- 2
- Both
- 6
AUC: number of occluded arteries (≥3) and high-grade enhancement (grade ≥2) identify patients with TAK at high risk for ischaemic stroke
- Number of occluded arteries (≥3) and high-grade enhancement (grade ≥2) can identify high-risk patients
Original publication
Clinical value of diagnosing ischaemic stroke in patients with Takayasu's arteritis combining multiple arterial occlusion and high-grade enhancement. Clin Exp Rheumatol. Published 4 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →