Inflammatory myopathies

Clinical relevance of positively determined myositis antibodies in rheumatology: a retrospective monocentric analysis

Arthritis Res TherPublished Retrospective cohort study

Authors' conclusion

In our cohort, we were able to show that a relevant proportion of patients with positive myositis antibodies did not have idiopathic inflammatory myopathies or inflammatory rheumatic diseases.

Study context

Population
Patients with positive myositis autoantibodies, Department of Rheumatology, Krankenhaus Porz am Rhein, Cologne, Germany, July 2019 to May 2022238 positive autoantibodies
Participants
209 patients
Outcome
Diagnoses in patients with positive myositis autoantibodies
Methodological detailsmonocentric, 71,597 laboratory values for myositis antibodies obtained
  • Monocentric
  • 71,597 laboratory values for myositis antibodies obtained

Main finding

As reported in the abstract

IIM diagnosed

37

18%

Inflammatory rheumatic diseases other than IIM

90

43%

No inflammatory rheumatic disease

82

39%

Observational data: associations, not effects.

Original publication

Clinical relevance of positively determined myositis antibodies in rheumatology: a retrospective monocentric analysis. Arthritis Res Ther. Published 16 July 2024. doi:10.1186/s13075-024-03368-9

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