Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care
Main finding · Proportion of patients in CDAI-based remissionResult — go to the resultHR for achieving remission 1.53 95% CI 1.11–2.10Authors' conclusion
Patients in our RA care pathway were more likely to achieve remission than those in usual care. PMPM RA costs were higher compared to usual care.
Study context
- Population
- Patients with rheumatoid arthritis (RA) at the Allegheny Health Network, a tertiary care integrated delivery network
- Participants
- 817 vs 3,651
- Exposure
- RA care pathway vs usual care
- RA care pathwayn = 817
- Usual caren = 3,651reference
- Outcome
- Proportion of patients in CDAI-based remission
- Follow-up
- 24 months
Methodological detailsclinical and insurance claims data, tertiary care integrated delivery network
- Clinical and insurance claims data
- Tertiary care integrated delivery network
Main finding
As reported in the abstract
HR for achieving remission
1.53
95% CI 1.11–2.10
P = 0.008
By group
RA care pathwayvs Usual care
HR for achieving remission 1.53 (95% CI 1.11–2.10); P = 0.008
- On average, remission occurred days earlier than usual care
- 64
Observational data: associations, not effects.
Further findings
Time to remission
- On average, remission occurred earlier with care pathway than usual care (days)
- 64
Remission or low disease activity; and newly diagnosed RA (subgroup)
- Same trend observed
RA-related per-member per-month (PMPM) costs
- Significantly higher in care pathway, primarily related to higher baseline clinical disease activity index (CDAI), comorbidities, and b/tsDMARD use and switching
Original publication
Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care. Arthritis Care Res (Hoboken). Published 16 December 2025. doi:10.
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