Clinical course of paediatric-onset Behçet’s disease in young adulthood
Authors' conclusion
Our results showed that nearly one-third of paediatric BD patients have a new major organ involvement or a relapse in adulthood.
Study context
- Population
- Patients diagnosed with Behçet's disease (BD) before the age of 18, five tertiary clinics; follow-up <6 months excluded68 with adulthood follow-up
- Participants
- 93 patients
- Outcome
- Clinical course of paediatric-onset BD in young adulthood (new major organ involvement or relapse in adulthood)
Methodological detailsmulticentre (five tertiary clinics)
- Multicentre (five tertiary clinics)
Main finding
As reported in the abstract
New major organ involvement or relapse during adulthood follow-up (of 68 with adult data)
New major organ involvement in adulthood
18
26.5%
Relapse in adulthood
9
13.2%
Observational data: associations, not effects.
Further findings
Major organ involvement during paediatric period
- Major organ involvement (overall)
- 49 (52.5%)
- Eye involvement (most common)
- 29%
- Median age at diagnosis, years
- 15 (13-17)
Patients with only mucocutaneous manifestations in paediatric period (n=40): new major organ involvement in adulthood
- New major organ involvement
- 15
- Mean time after diagnosis, years
- 10.1 (s.d.: 7.9)
- 53.3% were male
Patients with paediatric major organ involvement (n=28, 41.1%): new major organ involvement and/or relapse in adulthood
- New major organ involvement and/or relapse
- 12 (42.8%)
Original publication
Clinical course of paediatric-onset Behçet’s disease in young adulthood. Rheumatology (Oxford). Published 13 November 2024. doi:10.
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