Clinical Characteristics and Predictors of the Recurrence of Organizing Pneumonia Associated With Rheumatoid Arthritis
Authors' conclusion
RA-OP showed a high recurrence rate and was not associated with RA exacerbation. Four RA-OP recurrence predictors were identified.
Study context
- Population
- Patients with rheumatoid arthritis (RA)-associated organizing pneumonia (RA-OP) admitted to one hospital, 2006–2016
- Participants
- 33 patients
- Exposure
- Recurrent vs nonrecurrent RA-associated organizing pneumonia
- Recurrentn = 10
- Nonrecurrentn = 14reference
- Outcome
- Predictors of OP recurrence
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Patients with organizing pneumonia (OP) recurrence
10
30%
Interval between events
13.0 months
First OP recurrence rate
127/1000 person-years
Observational data: associations, not effects.
Further findings
| Outcome | HR | P value |
|---|---|---|
| Recurrence in OP-preceding patientsOP-preceding | 5.45 | P = 0.02 |
| Recurrence in OP-preceding patientsOP-preceding · 15 vs 136 months | P = 0.01 |
Clinical characteristics at OP onset
- RA onset preceded OP onset
- 82%
- OP onset preceded or co-occurred with RA (each)
- 9%
- Median age at first OP onset
- 64.0 years
- Period from RA onset to first OP onset
- 5.5 years
- Unilateral involvement
- 42%
- Normal Krebs von den Lungen-6
- 76%
- RA disease control optimal
- 52%
- RA exacerbated
- 18%
Original publication
Clinical Characteristics and Predictors of the Recurrence of Organizing Pneumonia Associated With Rheumatoid Arthritis. J Rheumatol. Published 1 August 2023. doi:10.
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