Lupus & antiphospholipid syndrome

Chorea associated with systemic lupus erythematosus- a systematic review

LupusPublished Systematic review

Authors' conclusion

Chorea is a rare manifestation in SLE and factors associated with its occurrence have not been addressed in cohort studies.

Study context

Population
Patients with systemic lupus erythematosus (SLE) in cohort studies and case/series reports60 cohort studies
Outcome
Prevalence and clinical and laboratory features associated with chorea in SLE
Methodological detailsPRISMA guidelines, PubMed and Scielo, September 1999–January 2024, English, Portuguese and Spanish, Investigation and treatment scheme proposed based on the literature review
  • PRISMA guidelines
  • PubMed and Scielo, September 1999–January 2024
  • English, Portuguese and Spanish
  • Investigation and treatment scheme proposed based on the literature review

Pooled result

As reported in the abstract

Pooled prevalence of chorea in SLE

Pooled prevalence of chorea in SLE

1.1%

Further pooled results

Timing and onset of chorea in case series and case reports

Chorea more frequent before or at SLE diagnosis
Chorea more frequent in childhood-onset SLE

Original publication

Chorea associated with systemic lupus erythematosus- a systematic review. Lupus. Published 20 May 2025. doi:10.1177/09612033251344045

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