Pediatric rheumatology

Characterizing the increasing trend of childhood-onset systemic lupus erythematosus in Bali and neighbouring provinces: Results of the Bali Paediatric Systemic Lupus Erythematosus Database (BEATLES) study

LupusPublished Retrospective cohort study

Authors' conclusion

cSLE demonstrates an increasing trend in Bali

Study context

Population
Systemic Lupus Erythematosus (SLE) patients <18 years, Department of Child Health, Prof. Ngoerah Hospital, Denpasar, Bali, 2009–2022
Exposure
Three subperiods: 2009-2014 vs 2015-2017 vs 2018-2022
Outcome
cSLE incidence trend, 2009-2022
Methodological detailshospital-based, single-centre
  • Hospital-based
  • Single-centre

Main finding

As reported in the abstract

  • A single case of cSLE in 2009, then a pause in new cases; incidence slowly increased until 2014
  • Surge in case numbers from 2015 to 2017
  • Incidence peaked in 2019, then declined, increasing again in 2022

Observational data: associations, not effects.

Further findings

Most common regency of origin

Denpasar in 1st period, Badung in 2nd, Denpasar in 3rd; referrals also from other provinces in 3rd period

Dominant age group

6-11 years in 1st period; 12-18 years, then 6-11 years, with a small number <5 years, in 2nd and 3rd periods

Sex ratio

No differences across the periods

Original publication

Characterizing the increasing trend of childhood-onset systemic lupus erythematosus in Bali and neighbouring provinces: Results of the Bali Paediatric Systemic Lupus Erythematosus Database (BEATLES) study. Lupus. Published 23 February 2026. doi:10.1177/09612033261428809

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