Cardiovascular risk assessment in idiopathic inflammatory myopathies: a multicentre international study by the myositis audit and research collaborative group
Authors' conclusion
Over a third of patients with IIM are at moderate-high-risk of cardiovascular events in 10 years. Steroid use and dyslipidaemia were modifiable risk factors that were statistically significant predictors of risk.
Study context
- Population
- Patients with idiopathic inflammatory myopathies (IIM) attending clinics 2020–2023 at centres in India, Hong Kong, Brazil, Italy, Australia and the UK
- Participants
- 336 patients
- Outcome
- CVD risk (WHO cardiovascular risk charts and QRISK3) and adherence to British Society for Rheumatology (BSR) and NICE guidelines
- Follow-up
- 10 years
Methodological detailsmulticentre, international, retrospective chart review, audit
- Multicentre
- International
- Retrospective chart review
- Audit
Main finding
As reported in the abstract
Moderate-high CVD risk (QRISK3)
Moderate-high risk patients prescribed a statin as per NICE guidelines
34 %
Observational data: associations, not effects.
Further findings
Factors associated with moderate-high risk scores
- IMNM subtype, OR (95% CI 1.88-11.45), p < 0.001
- 4.64
- Active steroid use, OR (95% CI 1.06-2.92), p = 0.03
- 1.76
- Dyslipidaemia, OR (95% CI 1.03-1.45), p = 0.02
- 1.22
Agreement between WHO and QRISK3 scores
- Moderate level of agreement
Original publication
Cardiovascular risk assessment in idiopathic inflammatory myopathies: a multicentre international study by the myositis audit and research collaborative group. Semin Arthritis Rheum. Published 17 December 2025. doi:10.
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