Systemic sclerosis & Raynaud's

Capi-score: a quantitative algorithm for identifying disease patterns in nailfold videocapillaroscopy

Rheumatology (Oxford)Published Diagnostic accuracy study

Authors' conclusion

The CAPI-score algorithm may become a tool that is useful in assigning DPs by overcoming the limitations of subjectivity.

Study context

Population
Nailfold videocapillaroscopy (NVC) specimens from SSc and RP patients examined by 9 capillaroscopistsNVCs (21,957 images)
Participants
851 participants
Outcome
CAPI-score algorithm accuracy for DP categorization
Methodological detailssoftware-based analysis, consensus reference (≥2 of 3 interobservers)
  • Software-based analysis
  • Consensus reference (≥2 of 3 interobservers)

Performance

As reported in the abstract

Rule 1, SSc vs non-SSc, accuracy

0.88

Rules 2 and 3, SSc-early vs SSc-active vs SSc-late, accuracy

0.82

Rule 4, non-SSc normal vs non-SSc non-specific, accuracy

0.73

Further findings

Accuracy in NVCs with full interobserver consensus

Accuracy improved when limited to NVCs with full consensus

Original publication

Capi-score: a quantitative algorithm for identifying disease patterns in nailfold videocapillaroscopy. Rheumatology (Oxford). Published 26 March 2024. doi:10.1093/rheumatology/keae197

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