Beliefs about medicines in gout patients: results from the NOR-Gout 2-year study
Authors' conclusion
Patient beliefs about medicines improved gradually over 2 years, with increased beliefs in the necessity of medication and reduced concerns, but this improvement was unrelated to better outcomes.
Study context
- Population
- Patients with a recent gout flare and increased serum urate
- Outcome
- Changes in beliefs about medicines (BMQ subscales: necessity, concerns, overuse, harm; necessity-concerns differential)
- Follow-up
- 2 years
Methodological detailssingle-group, nurse-led urate-lowering therapy (ULT) intervention with tight control visits and a treatment target
- Single-group
- Nurse-led ULT intervention with tight control visits and a treatment target
Main finding
As reported in the abstract
Necessity subscale, mean ± SD, increased from baseline to 2 years
17.0 ± 4.4 to 18.9 ± 3.6
p < 0.001
Concerns subscale, mean ± SD, decreased from baseline to 2 years
13.4 ± 4.9 to 12.5 ± 2.7
p = 0.001
Necessity-concerns differential increased, independent of achieving treatment targets at 1 or 2 years
3.52 to 6.58
p < 0.001
Observational data: associations, not effects.
Further findings
Mean serum urate · baseline to year 2
- Mean serum urate reduced, baseline to year 2
- 500 mmol/L to 324 mmol/L
Patients at treatment target · years 1 and 2
- At treatment target, year 1
- 85.5%
- At treatment target, year 2
- 78.6%
Original publication
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