Associations between the meniscal lesion parameters and knee joint structures and symptoms in patients with symptomatic knee osteoarthritis
Authors' conclusion
Meniscus lesion parameter values were associated with changes in knee structures and increases in knee symptoms
Study context
- Population
- Patients with symptomatic knee OA
- Participants
- 102 patients
- Outcome
- Associations of meniscal lesion parameters (Mean(MLD), Mean(RMLD)) with knee structures and symptoms
Methodological detailsmultivariate analyses
- Multivariate analyses
Main finding
As reported in the abstract
- Mean(MLD) vs total cartilage volume, β
- −0.008(−0.012, −0.003) (95% CI)
- Mean(MLD) vs MT cartilage volume, β
- −0.012(−0.017, −0.007) (95% CI)
- Mean(MLD) vs lateral tibial (LT) cartilage volume, β
- −0.006(−0.011, −0.001) (95% CI)
- Mean(MLD) vs lateral tibiofemoral joint (LTFJ)/medial tibiofemoral joint (MTFJ) cartilage defects and bone marrow lesions (BMLs), ORs
- 1.063-1.116(1.007-1.059 to 1.119-1.177) (95% CI)
- Mean(MLD) vs WOMAC score, β
- 2.145(1.160, 3.131) (95% CI)
- Mean(RMLD) vs total cartilage volume, β
- −0.005(−0.008, −0.002) (95% CI)
- Mean(RMLD) vs MT cartilage volume, β
- −0.008(−0.011, −0.004) (95% CI)
- Mean(RMLD) vs LT cartilage volume, β
- −0.005(−0.008, −0.001) (95% CI)
- Mean(RMLD) vs LTFJ/MTFJ cartilage defects and BMLs, ORs
- 1.046-1.086(1.008-1.044 to 1.082-1.123) (95% CI)
- Mean(RMLD) vs WOMAC score, β
- 1.465(0.793, 2.136) (95% CI)
Observational data: associations, not effects.
Original publication
Associations between the meniscal lesion parameters and knee joint structures and symptoms in patients with symptomatic knee osteoarthritis. Arthritis Res Ther. Published 3 June 2025. doi:10. 1186/ s13075-025-03583-y
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