Osteoarthritis

Associations between the meniscal lesion parameters and knee joint structures and symptoms in patients with symptomatic knee osteoarthritis

Arthritis Res TherPublished Cross-sectional study

Authors' conclusion

Meniscus lesion parameter values were associated with changes in knee structures and increases in knee symptoms

Study context

Population
Patients with symptomatic knee OA
Participants
102 patients
Outcome
Associations of meniscal lesion parameters (Mean(MLD), Mean(RMLD)) with knee structures and symptoms
Methodological detailsmultivariate analyses
  • Multivariate analyses

Main finding

As reported in the abstract

Mean(MLD) vs total cartilage volume, β
−0.008(−0.012, −0.003) (95% CI)
Mean(MLD) vs MT cartilage volume, β
−0.012(−0.017, −0.007) (95% CI)
Mean(MLD) vs lateral tibial (LT) cartilage volume, β
−0.006(−0.011, −0.001) (95% CI)
Mean(MLD) vs lateral tibiofemoral joint (LTFJ)/medial tibiofemoral joint (MTFJ) cartilage defects and bone marrow lesions (BMLs), ORs
1.063-1.116(1.007-1.059 to 1.119-1.177) (95% CI)
Mean(MLD) vs WOMAC score, β
2.145(1.160, 3.131) (95% CI)
Mean(RMLD) vs total cartilage volume, β
−0.005(−0.008, −0.002) (95% CI)
Mean(RMLD) vs MT cartilage volume, β
−0.008(−0.011, −0.004) (95% CI)
Mean(RMLD) vs LT cartilage volume, β
−0.005(−0.008, −0.001) (95% CI)
Mean(RMLD) vs LTFJ/MTFJ cartilage defects and BMLs, ORs
1.046-1.086(1.008-1.044 to 1.082-1.123) (95% CI)
Mean(RMLD) vs WOMAC score, β
1.465(0.793, 2.136) (95% CI)

Observational data: associations, not effects.

Original publication

Associations between the meniscal lesion parameters and knee joint structures and symptoms in patients with symptomatic knee osteoarthritis. Arthritis Res Ther. Published 3 June 2025. doi:10.1186/s13075-025-03583-y

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