Spondyloarthritis & psoriatic arthritis
Associations between loneliness, disease activity and disease impact in inflammatory arthritis: a nationwide cross-sectional study among more than 12 000 patients
Authors' conclusion
Loneliness was highly prevalent in IA and associated with disease activity and impact.
Study context
- Population
- Danish patients with IA (rheumatoid arthritis (RA)/psoriatic arthritis (PsA)/axial spondylarthritis (axSpA)) responding to a cross-sectional survey
- Participants
- 12,713 patients
- Exposure
- Loneliness prevalence across RA, PsA and axSpA, and by disease activity and impact
- Outcome
- Prevalence of loneliness ('Are you ever alone, although you would prefer to be together with others?')
Methodological detailsnationwide, survey linked to the DANBIO Rheumatology Registry and the National Patient Registry, multivariable logistic regression
- Nationwide
- Survey linked to the DANBIO Rheumatology Registry and the National Patient Registry
- Multivariable logistic regression
Main finding
As reported in the abstract
Prevalence of loneliness
RA
31.6%
95% CI 30.5–32.6
PsA
36.0
95% CI 34.0–38.0
axSpA
36.3
95% CI 34.1–38.4
Observational data: associations, not effects.
Further findings
- Loneliness in axSpA with high levels of depression (subgroup)
- 66.2% · CI 60.0–72.8
Association of loneliness with disease activity
- Positive association between loneliness and disease activity
Loneliness by disease impact (high pain, fatigue, PGA; low physical function)
- Prevalence estimates between 40% and 60%
Original publication
Associations between loneliness, disease activity and disease impact in inflammatory arthritis: a nationwide cross-sectional study among more than 12 000 patients. Rheumatology (Oxford). Published 11 September 2024. doi:10.
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