Association of Healthy Lifestyle Behaviors and the Risk of Developing Rheumatoid Arthritis Among Women
Main finding · Overall RA risk per higher (healthier) HLISResult — go to the resultHazard ratio 0.86 95% CI 0.82–0.90Authors' conclusion
In this prospective cohort, healthier lifestyle was associated with a lower RA risk.
Study context
- Population
- Female nurses in the Nurses' Health Study (NHS) (1986–2016) and NHSII (1991–2017)4,467,751 person-years
- Exposure
- Higher healthy lifestyle index score (HLIS) vs lower HLIS
- Outcome
- Incident RA, overall and by seropositive/seronegative subtype
Methodological detailsCox regression adjusted for confounders, medical record–confirmed rheumatoid arthritis (RA) and serostatus
- Cox regression adjusted for confounders
- Medical record–confirmed RA and serostatus
Main finding
Overall RA risk per higher (healthier) HLIS
Hazard ratio
0.86
95% CI 0.82–0.90
Higher HLIS
HR 0.86 (95% CI 0.82–0.90)
Per higher, as printed
As reported in the abstract
- Incident RA cases
- 1,219
Observational data: associations, not effects.
Further findings
Seropositive RA risk (776 cases)
| HR (95% CI) | ||
|---|---|---|
| Higher HLIS | 0.85 (0.80–0.91) | |
| 0.512Hazard ratio (log scale) |
Seronegative RA risk (443 cases)
| HR (95% CI) | ||
|---|---|---|
| Higher HLIS | 0.87 (0.80–0.94) | |
| 0.512Hazard ratio (log scale) |
RA risk with 5 healthy lifestyle factors (lowest risk)
| HR (95% CI) | ||
|---|---|---|
| 5 healthy lifestyle factors | 0.42 (0.22–0.80) | |
| 0.20.5125Hazard ratio (log scale) |
Population attributable risk for adhering to ≥4 lifestyle factors
- PAR for RA
- 34%
Original publication
Association of Healthy Lifestyle Behaviors and the Risk of Developing Rheumatoid Arthritis Among Women. Arthritis Care Res (Hoboken). Published 11 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →