Association of combined healthy lifestyle factors with incident osteoporosis in patients with and without type 2 diabetes
Authors' conclusion
Participants with T2DM who adhered to a variety of healthy lifestyle factors demonstrated a substantially reduced risk of developing OP.
Study context
- Population
- Middle-aged and older participants with and without type 2 diabetes; lifestyle score 0–7 from seven healthy lifestyle factors (no current smoking, non-excessive alcohol, regular physical activity, healthy diet, adequate sleep, less sedentary behaviour, adequate sunshine exposure)5,760 osteoporosis (OP) cases
- Participants
- 237,725 participants
- Exposure
- Combined healthy lifestyle score in participants with and without T2DM
- Outcome
- Incident osteoporosis
Methodological detailslongitudinal analysis
- Longitudinal analysis
Main finding
As reported in the abstract
Incident OP · median follow-up 12.21 years
Each group vs no diabetes, score 6-7Hazard ratio (95% CI)
T2DM, score 4
1.58(1.23–2.03)
T2DM, score 3
1.62(1.16–2.25)
T2DM, score 0-2
2.58(1.64–4.05)
Observational data: associations, not effects.
Further findings
Population attributable fraction for not adhering to 6-7 lifestyle behaviours
- Population attributable fraction
- 15.7%
Original publication
Association of combined healthy lifestyle factors with incident osteoporosis in patients with and without type 2 diabetes. Osteoporos Int. Published 21 May 2024. doi:10.
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