Lupus & antiphospholipid syndrome

Association of alcohol consumption and fatigue in systemic lupus erythematosus (SLE): A cross-sectional study from Lupus Registry of Nationwide Institution (LUNA) cohort

LupusPublished Cross-sectional study

Authors' conclusion

Frequent drinking was associated with less fatigue

Study context

Population
Patients with SLE from 10 institutions in Japan (LUNA cohort), 2018–2019 (median age 45 years; 87.3% female)580 after MI
Participants
534 patients
Exposure
Frequent vs moderate vs no alcohol consumption
  • Nonen = 326reference
  • Moderaten = 121
  • Frequentn = 87
Outcome
Lupus patient-reported outcomes (LupusPRO) Pain Vitality domain score (fatigue)
Methodological detailsmulticentre, multiple regression adjusted for age, sex and damage, sensitivity analysis after multiple imputation
  • Multicentre
  • Multiple regression adjusted for age, sex and damage
  • Sensitivity analysis after multiple imputation

Main finding

As reported in the abstract

β

5.98

95% CI 0.19–11.76

P = 0.04

Events by group

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association of alcohol consumption and fatigue in SLE: A cross-sectional study from Lupus Registry of Nationwide Institution (LUNA) cohort. Lupus. Published 21 February 2023. doi:10.1177/09612033231159471

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