Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Authors' conclusion
This study provides evidence of centrally mediated pain at the time of diagnosis, challenging the notion that, even at the early stage of disease, pain is driven only by peripheral mechanisms.
Study context
- Population
- Recently diagnosed patients with inflammatory arthritis (IA) with pain NRS scores of ≥357% female, 62% with RA
- Participants
- 61 participants
- Outcome
- Sensory profiles / pain characteristics
- Follow-up
- At diagnosis
Main finding
As reported in the abstract
- Peripheral joint inflammation
- 97%
- DAS28 score, mean ± SD
- 3.8 ± 1
- Met fibromyalgia criteria
- 21%
- painDETECT score ≥19
- 25%
- Tender minus swollen joint count ≥7 (significantly correlated with DAS28, MSK-HQ and PHQ-ADS scores)
- 20%
- QST: facilitated temporal pain summation
- 18%
- QST: deficient pain modulation
- 61%
Observational data: associations, not effects.
Original publication
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis. Arthritis Care Res (Hoboken). Published 7 October 2025. doi:10.
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