Autoinflammatory & rare systemic diseases
Anterior mediastinal lesions in TAFRO syndrome: potential clinical significance
Authors' conclusion
Anterior mediastinal lesions were more frequently observed in patients with TAFRO syndrome than in those with iMCD-NOS or FUO.
Study context
- Population
- Cases of TAFRO syndrome and idiopathic multicentric Castleman disease-not otherwise specified (iMCD-NOS) diagnosed at Tokyo Metropolitan Tama Medical Center, 2007–2024, and fever of unknown origin (FUO) patients, 2018–2024
- Participants
- 12 / 11 / 22
- Exposure
- TAFRO syndrome vs iMCD-NOS vs FUO later diagnosed as malignancy or autoimmune disorder
- TAFROn = 12
- iMCD-NOSn = 11
- FUOn = 22
- Outcome
- Anterior mediastinal lesion on body CT
Methodological detailssingle-centre, CT image review
- Single-centre
- CT image review
Main finding
As reported in the abstract
Anterior mediastinal lesion
Observational data: associations, not effects.
Original publication
Anterior mediastinal lesions in TAFRO syndrome: potential clinical significance. Rheumatology (Oxford). Published 16 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →