Analysis of clinical features and risk factors for patients with idiopathic inflammatory myopathy complicated by Pneumocystis jirovecii pneumonia
Authors' conclusion
Dermatomyositis, rash, decreased absolute lymphocyte count, and concurrent viral infection are independent risk factors for the occurrence of PJP in idiopathic inflammatory myopathy patients.
Study context
- Population
- Patients with IIM
- Participants
- 432 patients
- Exposure
- IIM with Pneumocystis jirovecii pneumonia (PJP) vs IIM without PJP
- PJP+IIMn = 34
- Outcome
- Independent risk factors for PJP occurrence
Methodological detailsunivariate and multiple logistic regression analysis, ROC curves for (1-3)-β-DG-glucan
- Univariate and multiple logistic regression analysis
- ROC curves for (1-3)-β-DG-glucan
Main finding
As reported in the abstract
Independent risk factors for PJP (multiple logistic regression)
- DM, rash, decreased absolute lymphocyte count and concurrent viral infection were the most important independent risk factors for PJP
Observational data: associations, not effects.
Further findings
Risk factors for PJP (univariate analysis)
- DM, anti-MDA5 antibodies, rash, concomitant respiratory symptoms, decreased absolute lymphocyte count, increased ESR, increased ferritin and concurrent bacterial or viral infections were risk factors for PJP
Original publication
Analysis of clinical features and risk factors for patients with idiopathic inflammatory myopathy complicated by Pneumocystis jirovecii pneumonia. Clin Exp Rheumatol. Published 6 February 2025. doi:10.
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