Adult-onset dermatomyositis is associated with an increased prevalence of diabetes mellitus independent of glucocorticoid use,
Main finding · Diabetes prevalenceResult — go to the resultOdds ratio 1.06Authors' conclusion
Adult-onset dermatomyositis is associated with a significantly higher prevalence of diabetes independent of glucocorticoid exposure
Study context
- Population
- Patients with adult-onset dermatomyositis in an institutional database, January 1, 2007 - December 31, 2021 (median age 64 years)median age 64 years
- Exposure
- Adult-onset DM vs matched non-DM controls
- Outcome
- Prevalence of diabetes (American Diabetes Association criteria)
Methodological detailspropensity-score matched (1:2) on age, sex, BMI, race, smoking status, hypertension and dyslipidemia, logistic regression
- Propensity-score matched (1:2) on age, sex, BMI, race, smoking status, hypertension and dyslipidemia
- Logistic regression
Main finding
Diabetes prevalence
Odds ratio
1.06
P = 0.008
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Timing of diabetes diagnosis relative to GC initiation
- Over half of diabetes diagnoses occurred before GC initiation
Diabetes risk factors in adult-onset dermatomyositis
- Higher BMI, hypertension and dyslipidemia significantly associated with diabetes
- Myositis-specific and associated antibodies not significantly associated
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Adult-onset dermatomyositis is associated with an increased prevalence of diabetes mellitus independent of glucocorticoid use,. Semin Arthritis Rheum. Published 19 June 2026. doi:10.
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