Adherence to treat-to-target recommendations in juvenile idiopathic arthritis in clinical practice
Authors' conclusion
PPGA is not consistently collected, hampering measurement-based care and T2T. PhGA and prior treatment steps are underlying current treatment decisions, but often not according to the T2T cut-offs and time-points that have been agreed upon in consensus.
Study context
- Population
- Children with juvenile idiopathic arthritis (JIA) in the UCAN JIA cohort (62% female, median age 10.0 years)
- Participants
- 476 children
- Outcome
- Adherence to Treat-to-Target (T2T) recommendations for JIA in clinical practice
- Follow-up
- six-months
Methodological detailsmulticentre, international, prospective
- Multicentre
- International
- Prospective
Main finding
As reported in the abstract
Adherence to T2T recommendations
Inactive arthritis based on AJC at six months
248 patients
52%
PPGA not collected
35%
In children with arthritis, treatment change as suggested in the recommendations made
33%
Observational data: associations, not effects.
Further findings
Treatment started at baseline
- NSAID and/or intra-articular injections
- 53%
- csDMARD
- 37%
- Biologic therapies
- 11%
Original publication
Adherence to treat-to-target recommendations in juvenile idiopathic arthritis in clinical practice. Pediatr Rheumatol Online J. Published 23 September 2026. doi:10.
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