Spondyloarthritis & psoriatic arthritis
Achieving inactive disease state in men and women with axial spondyloarthritis: results from a multi-country prospective observational study
Primary result · ASDAS LDA in nr-axSpAResult — go to the resultOdds ratio 2.23 95% CI 1.45–3.42Authors' conclusion
Women with nr-axSpA, but not r-axSpA, were less likely to achieve LDA and ID after 1 year than men.
Study context
- Population
- Patients with recently diagnosed (≤12 months) axial spondyloarthritis (axSpA), classified as r-axSpA or nr-axSpA by central radiograph readingsnr-axSpA 477
- Participants
- 1,385 patients
- Comparison
- Men vs women with recently diagnosed axSpA
- Primary endpoint
- ASDAS LDA and ID
- Follow-up
- 1 year
Methodological detailsmulti-country, 1-year
- Multi-country
- 1-year
Primary result
ASDAS LDA in nr-axSpA
Odds ratio
2.23
95% CI 1.45–3.42
P = 0.0002
By group
Menvs Women
OR 2.23 (95% CI 1.45–3.42); P = 0.0002
As reported in the abstract
Further findings
| Outcome | Men | Women | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| ASDAS ID in nr-axSpA · 1 year | 21.7% | 9.6% | 2.40 (1.39–4.12) | P = 0.0013 | |
| 0.20.5125Odds ratio (log scale) |
Baseline TNFi use in nr-axSpA
P = 0.0238
Baseline TNFi use in r-axSpA
P = 0.0118
TNFi use in r-axSpA · 1 year · not significantly higher for men in nr-axSpA
P = 0.0497
Axial Spondyloarthritis Disease Activity Score (ASDAS) low disease activity (LDA) and inactive disease (ID) in r-axSpA · 1 year
- No significant difference between men and women
Original publication
Achieving inactive disease state in men and women with axial spondyloarthritis: results from a multi-country prospective observational study. Rheumatology (Oxford). Published 20 August 2025. doi:10.
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