A tale of two regions: comparing clinical features and outcomes in pediatric enthesitis-related arthritis
Authors' conclusion
This study highlights notable differences in the clinical features and outcomes of ERA among Turkish and Tunisian children, emphasizing the potential influence of ethnic and regional factors on disease presentation and management.
Study context
- Population
- Children with Enthesitis-related Arthritis (ERA) from Istanbul Medical Faculty and Tunisia Kassab Institute (PReS Second Sister Hospital Initiative)
- Participants
- 94 children
- Exposure
- Tunisian vs Turkish children with ERA
- Tunisiann = 45
- Turkishn = 49
- Outcome
- Clinical features and outcomes
Methodological detailsmulticentre, international comparison
- Multicentre
- International comparison
Main finding
As reported in the abstract
- Biologics during disease course: nearly half of Turkish vs Tunisian
- 8.9%
- HLA-B27 positivity and age at disease onset (no influence)
- p = 0.45
- HLA-B27 positivity associated with longer diagnostic delay
- p < 0.001
Observational data: associations, not effects.
Original publication
A tale of two regions: comparing clinical features and outcomes in pediatric enthesitis-related arthritis. Pediatr Rheumatol Online J. Published 29 July 2025. doi:10.
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