Lupus & antiphospholipid syndrome

A structured primary care–led triage and referral pathway for systemic lupus erythematosus: Operational criteria and referral outcomes from a real-world rheumatology practice

LupusPublished Retrospective observational study

Authors' conclusion

A structured primary care-led triage pathway with explicit operational criteria provides a descriptive framework for risk-stratified referral to rheumatology care for patients with SLE in resource-constrained settings.

Study context

Population
Adults with confirmed systemic lupus erythematosus (SLE) managed January 2025–January 2026 at SERVIMED IPS, Colombia84.5% female
Participants
148 adults
Exposure
Continued primary care vs Programmed referral vs Prioritized referral vs Urgent referral
  • Programmed referraln = 38
  • Prioritized referraln = 55
  • Urgent referraln = 19
Outcome
Time to rheumatology assessment and indications for referral
Methodological detailssingle practice, four-level triage framework applied retrospectively, Triage pathway implemented by a family physician with postgraduate training in rheumatology
  • Single practice
  • Four-level triage framework applied retrospectively
  • Triage pathway implemented by a family physician with postgraduate training in rheumatology

Main finding

As reported in the abstract

Time to rheumatology assessment
Required rheumatology consultation (38 programmed, 55 prioritized)
93 (62.8%)
Required urgent referral
19 (12.8%)

Observational data: associations, not effects.

Further findings

OutcomeValues
Classification at Level 3, newly diagnosed vs established patientsNewly diagnosed 56.5% · Established 28.4%
SLEDAI-2KAvailable patients median 6 (IQR 4–10)
  • SLEDAI-2K: available in 92 patients

Triage reclassification

Occurred in a minority of cases

Original publication

A structured primary care–led triage and referral pathway for systemic lupus erythematosus: Operational criteria and referral outcomes from a real-world rheumatology practice. Lupus. Published 28 August 2026. doi:10.1177/09612033261484768

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