Systemic sclerosis & Raynaud's
A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis
Authors' conclusion
The hardness sensor showed greater reproducibility and accuracy than MRSS, and more application sites than durometer; it can also reflect patients' self-assessments and function test outcomes.
Study context
- Population
- Patients with SSc (skin induration)
- Comparison
- Hardness sensor vs mRSS and durometer
- Outcome
- Validity of a hardness sensor to assess skin induration: intraobserver and interobserver reliability, correlation with durometer and mRSS, sensitivity to change
Methodological detailsLatin square experiment, longitudinal cohort
- Latin square experiment
- Longitudinal cohort
Performance
As reported in the abstract
Reliability (intraobserver; interobserver intraclass correlation coefficients)
| Test or model | Intraobserver ICC | Interobserver ICC |
|---|---|---|
| Hardness sensor | 0.97 | 0.96 |
| Modified Rodnan skin score (MRSS) | 0.86 | 0.74 |
Intraobserver ICC
Hardness sensor0.97
Modified Rodnan skin score (MRSS)0.86
Interobserver ICC
Hardness sensor0.96
Modified Rodnan skin score (MRSS)0.74
- Hardness sensor interobserver reproducibility poor only in abdomen
- 0.38
- Durometer interobserver reproducibility poor in face
- 0.11
- Durometer interobserver reproducibility poor in abdomen
- 0.33
Further findings
Correlation of total hardness sensor score
- With MRSS
- r=0.90, p<0.001
- With total durometer score
- r=0.95, p<0.001
- With HAQ-DI
- r=0.70, p<0.001
- With KTF score
- r=0.66, p<0.001
Correlation of change in hardness sensor score (sensitivity to change)
- With change in MRSS
- r=0.78, p<0.001
- With total durometer score
- r=0.85, p<0.001
- With HAQ-DI
- r=0.76, p<0.001
- With KTF score
- r=0.67, p<0.001
Original publication
A stretchable hardness sensor for the assessment of skin disease in systemic sclerosis. RMD Open. Published 23 November 2023. doi:10.
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