Work productivity and activity impairment in patients under 18 with juvenile idiopathic arthritis (JIA): the international UCAN CAN-DU prospective study
Authors' conclusion
There are substantial impacts on the ability of youth to be fully productive at work, affecting overall work impairment. In addition, there was substantial impairment in usual activities.
Study context
- Population
- Patients under 18 with JIA of all sub-types in the Canada-Netherlands Personalized Medicine Network in Childhood Arthritis and Rheumatic Diseases (UCAN CAN-DU) cohort (median age 17 years, 66% female)≥1 WPAI-SHP response
- Participants
- 154 participants
- Outcome
- Work productivity and activity impairment due to JIA (WPAI-SHP): absenteeism, presenteeism, overall work impairment, activity impairment
- Follow-up
- Up to 12 months from enrollment
Methodological detailsinternational, multicentre, generalized estimating equations adjusted for disease activity (cJADAS10)
- International
- Multicentre
- Generalized estimating equations adjusted for disease activity (cJADAS10)
Main finding
As reported in the abstract
WPAI-SHP impairment due to JIA · up to 12 months
Absenteeism (mean % work time missed)
7%
Presenteeism (% work impaired while at work)
27%
Overall work impairment
23%
Activity impairment
29%
Observational data: associations, not effects.
Further findings
Impairment by disease activity and over time
- More severe JIA: greater absenteeism, and work and activity impairment
- Work and activity impairment persistent over time
Original publication
Work productivity and activity impairment in patients under 18 with juvenile idiopathic arthritis (JIA): the international UCAN CAN-DU prospective study. Arthritis Res Ther. Published 27 March 2026. doi:10.
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