Rheumatoid arthritis

Vehicle Control as a Measure of Real‐World Driving Performance in Patients With Rheumatoid Arthritis

Arthritis Care Res (Hoboken)Published Prospective cohort study

Authors' conclusion

Using novel naturalistic assessments, we linked RA and worsening RA disease severity with aberrant vehicle control.

Study context

Population
Patients with active rheumatoid arthritis (RA) and controls without disease, driving their own vehicles1,292 driving hours
Participants
33 vs 23
Exposure
Active RA vs controls without disease
  • RAn = 33
  • Controlsn = 23reference
Outcome
Vehicle control: lateral (steering) and longitudinal (braking/accelerating) acceleration variability
Methodological detailsnaturalistic driving assessment, in-car sensor-based instrumentation, mixed-effect linear regression stratified by road type
  • Naturalistic driving assessment
  • In-car sensor-based instrumentation
  • Mixed-effect linear regression stratified by road type

Main finding

As reported in the abstract

Vehicle control by road type
Interaction between disease status and road type
P < 0.001
Residential roads: RA overall lower braking/accelerating variability than controls
P ≤ 0.004
Residential roads, low disease activity: RA lower steering variability
P = 0.03
Interstates/highways: RA with moderate/high CDAI increased steering variability
P = 0.04

Observational data: associations, not effects.

Further findings

Within RA: increases in disease activity and physical disability over 12 weeks vs braking/accelerating variability on interstates/highways

Significant increase in braking/accelerating variability (both)
P < 0.05

Original publication

Vehicle Control as a Measure of Real‐World Driving Performance in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 23 September 2022. doi:10.1002/acr.24769

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