Ultrasound of the forefeet besides the hands in patients at risk for rheumatoid arthritis: is it worth the effort? A longitudinal cohort study
Authors' conclusion
The forefeet can be omitted when US is used for the prediction of RA-development in CSA patients.
Study context
- Population
- Patients with clinically suspect arthralgia (CSA)
- Participants
- 298 patients2 cohorts
- Exposure
- Full US protocol (hands and forefeet) vs full protocol with correction for gray scale (GS) findings in forefeet of healthy vs protocol without forefeet
- Outcome
- Association between US-positivity and RA/inflammatory arthritis development
Methodological detailstwo independent cohorts
- Two independent cohorts
Main finding
As reported in the abstract
Inflammatory arthritis development by US-positivity, per US-protocol, in both cohorts
- AUROCs were equal across both cohorts
Observational data: associations, not effects.
Further findings
Location of subclinical joint-inflammation in US-positive patients
- Mostly present in the hands
- 90-86%
- Solely in the forefeet
- 10-14%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Ultrasound of the forefeet besides the hands in patients at risk for rheumatoid arthritis: is it worth the effort? A longitudinal cohort study. Rheumatology (Oxford). Published 19 June 2024. doi:10.
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