Lupus & antiphospholipid syndrome
Therapeutic Hydroxychloroquine Blood Levels Are Associated With Fewer Hospitalizations and Possible Reduction of Health Disparities in Lupus
Authors' conclusion
HCQ blood levels within 750 to 1,200 ng/mL are associated with lower rates of acute care in all patients with lupus, including groups with higher rates of acute care.
Study context
- Population
- Patients with lupus with hydroxychloroquine (HCQ) blood levels measured during routine lupus visits
- Participants
- 181 patients39 acute care visits
- Exposure
- Therapeutic vs subtherapeutic or supratherapeutic HCQ blood levels
- Outcome
- Time to first lupus-related acute care visit (ED visits/hospitalizations)
Main finding
As reported in the abstract
Lupus-related acute care
Therapeutic HCQ blood levels associated with lower rates of acute care
66% lower
Observational data: associations, not effects.
Further findings
- Higher rates of acute care in Black or Hispanic patients and those with public insurance
- three to four times higher
- Levels within 750 to 1,200 ng/mL associated with lower rates of acute care use in these subgroups
- 95% lower
Original publication
Therapeutic Hydroxychloroquine Blood Levels Are Associated With Fewer Hospitalizations and Possible Reduction of Health Disparities in Lupus. Arthritis Care Res (Hoboken). Published 1 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →