Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis
Authors' conclusion
Self-reported poor sleep duration, efficiency, and quality were significantly associated with fatigue in patients with RA, whereas objective actigraphy-based sleep parameters were not
Study context
- Population
- Adult patients with rheumatoid arthritis (RA) from a single academic rheumatology practice
- Participants
- 48 patients
- Outcome
- Association of subjective (self-reported) and objective (actigraphy-based) sleep parameters with self-reported fatigue (PROMIS fatigue)
Methodological detailssingle academic rheumatology practice, 14-day actigraphy and sleep diary
- Single academic rheumatology practice
- 14-day actigraphy and sleep diary
Main finding
As reported in the abstract
Correlation of subjective sleep parameters with PROMIS fatigue (Spearman)
Longer total sleep time associated with lower fatigue, ρ
−0.4
P < 0.01
Higher sleep efficiency associated with lower fatigue, ρ
−0.42
P < 0.01
Better sleep quality associated with lower fatigue, ρ
−0.5
P < 0.01
Observational data: associations, not effects.
Further findings
Subjective sleep parameters and fatigue, linear regression adjusted for swollen joint count, pain intensity and depression symptoms
- Each subjective sleep parameter remained significantly associated with fatigue after adjustment
Original publication
Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 7 August 2025. doi:10. 1002/ acr. 25579
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