Rheumatoid arthritis

Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

Self-reported poor sleep duration, efficiency, and quality were significantly associated with fatigue in patients with RA, whereas objective actigraphy-based sleep parameters were not

Study context

Population
Adult patients with rheumatoid arthritis (RA) from a single academic rheumatology practice
Participants
48 patients
Outcome
Association of subjective (self-reported) and objective (actigraphy-based) sleep parameters with self-reported fatigue (PROMIS fatigue)
Methodological detailssingle academic rheumatology practice, 14-day actigraphy and sleep diary
  • Single academic rheumatology practice
  • 14-day actigraphy and sleep diary

Main finding

As reported in the abstract

Correlation of subjective sleep parameters with PROMIS fatigue (Spearman)

Longer total sleep time associated with lower fatigue, ρ

−0.4

P < 0.01

Higher sleep efficiency associated with lower fatigue, ρ

−0.42

P < 0.01

Better sleep quality associated with lower fatigue, ρ

−0.5

P < 0.01

Observational data: associations, not effects.

Further findings

Subjective sleep parameters and fatigue, linear regression adjusted for swollen joint count, pain intensity and depression symptoms

Each subjective sleep parameter remained significantly associated with fatigue after adjustment

Original publication

Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 7 August 2025. doi:10.1002/acr.25579

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