Systemic sclerosis & Raynaud's

Scleroderma clinical trials consortium classification criteria for systemic sclerosis heart involvement

Rheumatology (Oxford)Published Classification criteria development and validation study

Authors' conclusion

The newly derived SCTC SHI Classification Criteria have high sensitivity and specificity for SHI.

Study context

Population
Independent cohort of SHI cases and non-SSc heart disease controlsvalidation cohort
Participants
168 participants
Comparison
SHI vs non-SSc heart disease
Outcome
Sensitivity and specificity of the SCTC SHI classification criteria
Methodological detailsconsensus methods, discrete choice experiment, international, interdisciplinary working group, independent validation cohort
  • Consensus methods
  • Discrete choice experiment
  • International, interdisciplinary working group
  • Independent validation cohort

Performance

As reported in the abstract

Classification of SHI vs non-SSc heart disease controls, independent cohort
Test or modelSensitivitySpecificityAUC
Criteria score ≥1178%96%0.87 (0.80-0.93)

Criteria score ≥11

Sensitivity78%
Specificity96%
AUC0.87 (0.80-0.93)

Original publication

Scleroderma clinical trials consortium classification criteria for systemic sclerosis heart involvement. Rheumatology (Oxford). Published 27 February 2026. doi:10.1093/rheumatology/keag109

Composed by AI from the published abstract and checked against it. How Briefs are made →

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