Systemic sclerosis & Raynaud's
Scleroderma clinical trials consortium classification criteria for systemic sclerosis heart involvement
Authors' conclusion
The newly derived SCTC SHI Classification Criteria have high sensitivity and specificity for SHI.
Study context
- Population
- Independent cohort of SHI cases and non-SSc heart disease controlsvalidation cohort
- Participants
- 168 participants
- Comparison
- SHI vs non-SSc heart disease
- Outcome
- Sensitivity and specificity of the SCTC SHI classification criteria
Methodological detailsconsensus methods, discrete choice experiment, international, interdisciplinary working group, independent validation cohort
- Consensus methods
- Discrete choice experiment
- International, interdisciplinary working group
- Independent validation cohort
Performance
As reported in the abstract
Classification of SHI vs non-SSc heart disease controls, independent cohort
| Test or model | Sensitivity | Specificity | AUC |
|---|---|---|---|
| Criteria score ≥11 | 78% | 96% | 0.87 (0.80-0.93) |
Criteria score ≥11
Sensitivity78%
Specificity96%
AUC0.87 (0.80-0.93)
Original publication
Scleroderma clinical trials consortium classification criteria for systemic sclerosis heart involvement. Rheumatology (Oxford). Published 27 February 2026. doi:10. 1093/ rheumatology/ keag109
Composed by AI from the published abstract and checked against it. How Briefs are made →