SARS-CoV-2 infection among patients with autoimmune rheumatic diseases; comparison between the Delta and Omicron waves in Israel
Main finding · COVID-19-related hospitalizationResult — go to the resultRelative risk 0.4 95% CI 0.27–0.59Authors' conclusion
ARD patients infected with the COVID-19 Omicron variant had a lower risk of developing COVID-19-related adverse outcomes compared to the Delta variant.
Study context
- Population
- Actively treated Autoimmune Rheumatic Disease (ARD) patients diagnosed with COVID-19, Clalit Health Services, Israel
- Participants
- 7,249 vs 1,204
- Exposure
- Omicron vs Delta variant wave
- Omicronn = 7,249
- Deltan = 1,204reference
- Outcome
- COVID-19-related hospitalization or death
Methodological detailsmultivariable regression models
- Multivariable regression models
Main finding
COVID-19-related hospitalization
Relative risk
0.4
95% CI 0.27–0.59
P < 0.001
By group
Omicronvs Delta
RR 0.4 (95% CI 0.27–0.59); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Delta | Omicron | RR (95% CI) | P value | |
|---|---|---|---|---|---|
| COVID-19-related deathMultivariable regression; p for crude rate comparison | 3.2% | 1.1% | 0.48 (0.31–0.75) | P < 0.001 | |
| 0.20.5125Relative risk (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
SARS-CoV-2 infection among patients with autoimmune rheumatic diseases; comparison between the Delta and Omicron waves in Israel. Semin Arthritis Rheum. Published 21 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →