Lupus & antiphospholipid syndrome
Salivary proteomics profiling in cutaneous lupus erythematosus
Authors' conclusion
This study establishes a distinct salivary proteomic signature in CLE, highlighting proteins with diagnostic potential.
Study context
- Population
- Females with CLE and controls without autoimmune conditions; saliva samples
- Exposure
- CLE vs healthy controls
- CLEn = Ten
- Controlsn = elevenreference
- Outcome
- Salivary proteomic profile of CLE vs healthy controls
Methodological detailscase-control, mass spectrometry proteomics
- Case-control
- Mass spectrometry proteomics
Main finding
As reported in the abstract
Salivary proteins (104 identified)
Proteins with statistically significant differences between groups
6
PEBP1 and ARG1 discriminatory power, AUROC
1.0
Observational data: associations, not effects.
Original publication
Salivary proteomics profiling in cutaneous lupus erythematosus. Lupus. Published 18 December 2025. doi:10. 1177/ 09612033251407232
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