Risk factors affecting the vital prognosis in patients with rheumatoid arthritis after primary cervical spine surgery: a retrospective study
Authors' conclusion
SAS comorbidity, high-dose prednisolone administration, lower serum albumin levels, and advanced age exacerbate the vital prognosis in patients with RA requiring primary cervical spine surgery.
Study context
- Population
- Patients with rheumatoid arthritis (RA) who underwent primary cervical spine surgery for cervical spine lesions, January 2001 to December 2020
- Participants
- 139 patients
- Outcome
- Vital prognosis (survival) and risk factors for a poor vital prognosis
- Follow-up
- 10 years
Methodological detailsunivariate and multivariate Cox regression, Kaplan-Meier method
- Univariate and multivariate Cox regression
- Kaplan-Meier method
Main finding
As reported in the abstract
Vital prognosis (Kaplan-Meier)
Vital prognosis at 10 years
62.7%
Observational data: associations, not effects.
Further findings
Univariate risk factors for mortality
- Advanced age, lower serum albumin, high-dose prednisolone, non-use of MTX and subaxial subluxation (SAS) comorbidity significantly associated with high mortality risk
Original publication
Risk factors affecting the vital prognosis in patients with rheumatoid arthritis after primary cervical spine surgery: a retrospective study. Arthritis Res Ther. Published 1 July 2025. doi:10. 1186/ s13075-025-03593-w
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