Rheumatoid arthritis

Risk factors affecting the vital prognosis in patients with rheumatoid arthritis after primary cervical spine surgery: a retrospective study

Arthritis Res TherPublished Retrospective cohort study

Authors' conclusion

SAS comorbidity, high-dose prednisolone administration, lower serum albumin levels, and advanced age exacerbate the vital prognosis in patients with RA requiring primary cervical spine surgery.

Study context

Population
Patients with rheumatoid arthritis (RA) who underwent primary cervical spine surgery for cervical spine lesions, January 2001 to December 2020
Participants
139 patients
Outcome
Vital prognosis (survival) and risk factors for a poor vital prognosis
Follow-up
10 years
Methodological detailsunivariate and multivariate Cox regression, Kaplan-Meier method
  • Univariate and multivariate Cox regression
  • Kaplan-Meier method

Main finding

As reported in the abstract

Vital prognosis (Kaplan-Meier)

Vital prognosis at 10 years

62.7%

Observational data: associations, not effects.

Further findings

Univariate risk factors for mortality

Advanced age, lower serum albumin, high-dose prednisolone, non-use of MTX and subaxial subluxation (SAS) comorbidity significantly associated with high mortality risk

Original publication

Risk factors affecting the vital prognosis in patients with rheumatoid arthritis after primary cervical spine surgery: a retrospective study. Arthritis Res Ther. Published 1 July 2025. doi:10.1186/s13075-025-03593-w

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