Rheumatoid arthritis

Psychological distress over 12 months post-diagnosis in an early inflammatory arthritis cohort

Rheumatology (Oxford)Published Prospective cohort study

Authors' conclusion

Half of patients with IA show significant mental health comorbidity at presentation, which associated with worse disease outcomes and quality of life.

Study context

Population
People recruited to the National Early Inflammatory Arthritis Audit (NEIAA) receiving an inflammatory arthritis (IA) diagnosis and completing the baseline patient survey
Participants
6,873 eligible patients
Outcome
Psychological distress (Patient Health Questionnaire Anxiety and Depression Screener (PHQ4ADS))
Follow-up
Baseline, 3 months and 12 months
Methodological detailsmixed effects linear regression
  • Mixed effects linear regression

Main finding

As reported in the abstract

baseline

Distressed at baseline

3451

50.2%

Observational data: associations, not effects.

Further findings

Psychological distress among those completing follow-ups · 3 months and 12 months

Distressed at 3 months
30.0%
Distressed at 12 months
24.1%

Predictors of higher distress at diagnosis · baseline

Higher distress more commonly reported by younger, female and non-White patients
Higher comorbidity counts, prior depression and higher disease activity at diagnosis associated with higher distress

Outcomes over time by baseline distress

Higher baseline distress associated with poorer quality of life, disability, work performance, disease activity, and reduced likelihood of good EULAR treatment response

Original publication

Psychological distress over 12 months post-diagnosis in an early inflammatory arthritis cohort. Rheumatology (Oxford). Published 15 May 2024. doi:10.1093/rheumatology/keae276

Composed by AI from the published abstract and checked against it. How Briefs are made →

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