Autoinflammatory & rare systemic diseases

Predictive factors of comorbid attention-deficit/hyperactivity disorder in early systemic autoimmune and auto-inflammatory disorders

Pediatr Rheumatol Online JPublished Case-control study

Study context

Population
Patients with early systemic autoimmune and autoinflammatory disorders (ESAID) and/or ADHD
Participants
14 / 14 / 35
Comparison
ESAID patients with ADHD vs ESAID patients without ADHD and ADHD patients without ESAID
  • ESAID+/ADHD+n = 14
  • ESAID+/ADHD-n = 14reference
  • ESAID-/ADHD+n = 35reference
Outcome
Natural history of ADHD comorbidity and other neurodevelopmental disorders (NDD) risk factors in ESAID
Methodological detailsESAID cohort (ARTEMIS) and ADHD cohort (Robert Debre)
  • ESAID cohort (ARTEMIS) and ADHD cohort (Robert Debre)

Main finding

As reported in the abstract

  • Onset of ADHD in ESAID associated with global cognitive brain impairment, not apparently due to shared genetic risk factors
  • Low birth weight contributes to development of ADHD in ESAID patients

Observational data: associations, not effects.

Original publication

Predictive factors of comorbid attention-deficit/hyperactivity disorder in early systemic autoimmune and auto-inflammatory disorders. Pediatr Rheumatol Online J. Published 2 June 2025. doi:10.1186/s12969-025-01103-5

Composed by AI from the published abstract and checked against it. How Briefs are made →

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