Preconception clinical factors related to adverse pregnancy outcomes in patients with systemic lupus erythematosus or primary Sjögren’s syndrome: a retrospective cohort study
Authors' conclusion
No preconception risk factors related to APO were found in SLE pregnancies, whereas preconception complement levels were associated with APO development in patients with pSS.
Study context
- Population
- Pregnant women with systemic lupus erythematosus (SLE) or primary Sjögren's syndrome (pSS) treated at the University Medical Center Groningen, January 2010 to August 202170 fetuses (one twin)
- Outcome
- Associations between preconception clinical factors and APO
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- pSS: association between APO and BMI
- p=0.010
- pSS: association between APO and parity
- p=0.046
- pSS: association between APO and C4
- p=0.021
- pSS: association between APO and low C4 levels
- p=0.002
Observational data: associations, not effects.
Further findings
Most frequent APO
APO SLE Preterm birth · pSS Miscarriages
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Preconception clinical factors related to adverse pregnancy outcomes in patients with systemic lupus erythematosus or primary Sjögren’s syndrome: a retrospective cohort study. RMD Open. Published 31 August 2023. doi:10.
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