Osteoporosis & bone health

Post-fracture care and predictors of anti-osteoporotic treatment in Switzerland: a nationwide health claims analysis

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Osteoporosis treatment rates after hip and vertebral fractures were low, with 88% and 77% of patients, respectively, not receiving treatment within 6 months.

Study context

Population
Hospitalised patients aged ≥ 50 years with recent vertebral, hip or other fractures, claims data from the largest Swiss health insurance provider, 2021–2023
Participants
6,229 / 2,458 / 11,314
Exposure
Hip fractures vs Vertebral fractures vs Other fractures
  • Hip fracturesn = 6,229
  • Vertebral fracturesn = 2,458
  • Other fracturesn = 11,314
Outcome
Treatment rates and predictors of anti-osteoporotic therapies post-fracture
Follow-up
12 months
Methodological detailsnationwide health claims analysis
  • Nationwide health claims analysis

Main finding

As reported in the abstract

Anti-osteoporotic treatment rate · within 6 months post-fracture

Anti-osteoporotic treatment rate · within 6 months post-fracture

Denosumab Hip fractures 5.0% · Vertebral fractures 9.4%

Zoledronate Hip fractures 2.6% · Vertebral fractures 4.7%

Alendronate Hip fractures 2.1%

Already on therapy before fracture

Ibandronate Vertebral fractures 3.6%

Anabolic agents Vertebral fractures 2.7%

Not receiving treatment within 6 months: hip fractures
88%
Not receiving treatment within 6 months: vertebral fractures
77%

Observational data: associations, not effects.

Further findings

Strongest predictor of treatment initiation: DXA scan

OR (CI)
DXA scan10.2 (9.1–11.5)

Already receiving osteoporosis therapy before the fracture

Strongest predictor of treatment initiation: DXA scan

Female sex, older age and greater comorbidity showed weaker effects

Care trajectories · within 3 months post-fracture

Inpatient rehabilitation required
8-11%
Newly transitioned to nursing home placement
18-21%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Post-fracture care and predictors of anti-osteoporotic treatment in Switzerland: a nationwide health claims analysis. Osteoporos Int. Published 12 January 2026. doi:10.1007/s00198-025-07832-3

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