Osteoporosis & bone health

Patients with periprosthetic femoral fractures are older adults who are commonly diagnosed with osteoporosis

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Low-energy PFF should be considered as an osteoporotic fracture and treated accordingly.

Study context

Population
Patients aged ≥ 50 years with low-energy PFF, Lille University Hospital, January 1, 2016 to December 31, 2022
Participants
71 vs 117
Exposure
PFF vs native hip fractures
  • PFFn = 71
  • Native hip fracturen = 117reference
Outcome
Adjusted bone mineral density (BMD) T-scores
Methodological detailssingle-centre, observational, linear mixed model adjusted for age, sex and BMI
  • Single-centre
  • Observational
  • Linear mixed model adjusted for age, sex and BMI

Main finding

As reported in the abstract

Adjusted T-score, lumbar spine

PFF

- 0.5

mean adjusted · SE 0.2

Native hip fracture

- 1.2

mean adjusted · SE 0.2

P = 0.008

Observational data: associations, not effects.

Further findings

History of multiple falls

P < 0.001

Previous low-energy fractures

P < 0.001

Anti-osteoporosis medication prescription

P = 0.006

Age and BMI · significantly older
P = 0.002
Age and BMI · significantly greater BMI
P = 0.043

Original publication

Patients with periprosthetic femoral fractures are older adults who are commonly diagnosed with osteoporosis. Osteoporos Int. Published 29 April 2025. doi:10.1007/s00198-025-07486-1

Composed by AI from the published abstract and checked against it. How Briefs are made →

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