Paraneoplastic arthritis: a series of 92 cases
Authors' conclusion
Although PA is a rare condition, it can be confused with many rheumatological diseases. The most commonly involved joint is the knee joint, followed by the ankle and hand/wrist. Autoantibody negativity, high lactate dehydrogenase level and arthritis unresponsive to treatment constitute important clues for diagnosis.
Study context
- Population
- Patients with paraneoplastic arthritis from the last 10 years
- Participants
- 92 patients
- Exposure
- Paraneoplastic arthritis (PA) vs Healthy control
- PAn = 92
- Outcome
- Malignancy types in PA
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Lymphomas among PA with haematological malignancies (highest ratio)
25.6%
Lung cancer among PA with solid malignancy (most common)
41.5%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Anti-CCP positivity | P = 0.014 |
- Anti-CCP positivity: all malignant patients with PA had significant anti-CCP positivity vs healthy controls
Original publication
Paraneoplastic arthritis: a series of 92 cases. Rheumatology (Oxford). Published 21 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →