Pan American League of Associations for Rheumatology recommendations for the management of rheumatoid arthritis
Methodological detailsGRADE method, systematic literature reviews, expert consensus (≥70% agreement)
- GRADE method
- Systematic literature reviews
- Expert consensus (≥70% agreement)
Recommendations
As issued by the authors
Early initiation of csDMARDs, particularly MTX
Parenteral MTX for intolerance
Cautious GC use
Switching mechanisms of action after unsuccessful b/tsDMARD treatment
Tapering in remission
Guidance for RA-associated ILD and vasculitis
Original publication
Pan American League of Associations for Rheumatology recommendations for the management of rheumatoid arthritis. Lancet Rheumatol. Published 12 November 2025. doi:10.
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