Osteoporosis & bone health

Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Lumbar fractures and/or multiple fractures at the lumbar or thoracolumbar regions are risk factors for sagittal malalignment in patients older than 70 years old.

Study context

Population
Patients older than 70 years diagnosed with osteoporosis with chronic vertebral fractures673 chronic fractures
Participants
249 participants
Outcome
Sagittal alignment and risk factors for sagittal malalignment

Main finding

As reported in the abstract

Mean number of vertebral fractures per patient

2.7 ± 1.9

Patients with sagittal malalignment

41

Lumbar fractures in malalignment subpopulation vs overall

34% vs. 11%

Thoracic fractures in malalignment subpopulation vs overall

9% vs. 34%

Observational data: associations, not effects.

Original publication

Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment. Osteoporos Int. Published 13 October 2023. doi:10.1007/s00198-023-06936-y

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