Optical coherence tomography for the screening of anterior chamber inflammation in paediatric patients diagnosed with juvenile idiopathic arthritis
Authors' conclusion
AS-OCT could be considered for the screening of anterior segment uveitis in children diagnosed with JIA.
Study context
- Population
- Juvenile idiopathic arthritis (JIA) patients younger than 18 years300 eyes
- Participants
- 150 participants
- Comparison
- Anterior segment optical coherence tomography (AS-OCT) vs slit-lamp examination for anterior uveitis
- Outcome
- Effectiveness of AS-OCT for screening of anterior uveitis
Methodological detailscross-sectional, observational, non-randomised
- Cross-sectional
- Observational
- Non-randomised
Performance
As reported in the abstract
Anterior uveitis detection (eyes)
| Test or model | Value | Sensitivity | Specificity | PPV | NPV | Kappa-Cohen index |
|---|---|---|---|---|---|---|
| AS-OCT | 27 events | 0.94 | 0.96 | 0.59 | 0.99 | 0.71 |
| Slit-lamp | 16 events |
Value
AS-OCT27 events
Slit-lamp16 events
Sensitivity
AS-OCT0.94
Slit-lamp— not stated in the abstract
Specificity
AS-OCT0.96
Slit-lamp— not stated in the abstract
PPV
AS-OCT0.59
Slit-lamp— not stated in the abstract
NPV
AS-OCT0.99
Slit-lamp— not stated in the abstract
Kappa-Cohen index
AS-OCT0.71
Slit-lamp— not stated in the abstract
Further findings
AS-OCT findings (eyes)
- Cells detected
- 27
- Retrokeratic precipitates
- 5
Original publication
Optical coherence tomography for the screening of anterior chamber inflammation in paediatric patients diagnosed with juvenile idiopathic arthritis. Clin Exp Rheumatol. Published 7 November 2023. doi:10.
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