Osteoporosis & bone health

National trends in osteoporosis medication use among Medicare beneficiaries with and without Alzheimer’s disease/related dementias

Osteoporos IntPublished Retrospective cohort study

Main finding · OP drug useResult — go to the resultOdds ratio 0.85 95% CI 0.83–0.87

Authors' conclusion

ADRD patients received OP drugs at a lower rate than their non-ADRD counterparts.

Study context

Population
Medicare beneficiaries with osteoporosis (OP) aged ≥ 67 years with Medicare parts A/B/D without HMO, 2016–2018
Participants
47,871 vs 201,840
Exposure
And related dementia (ADRD) vs non-ADRD
  • ADRDn = 47,871
  • Non-ADRDn = 201,840reference
Outcome
Receipt of OP medications
Follow-up
2018
Methodological detailsmultivariable logistic regression, Medicare claims
  • Multivariable logistic regression
  • Medicare claims

Main finding

OP drug use

Odds ratio

0.85

95% CI 0.83–0.87

By group

ADRDvs non-ADRD
OR 0.85 (95% CI 0.83–0.87)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
OP drug use by ADRD, community-dwelling elders (subgroup)Significant ADRD × NH residency and ADRD × age interactions0.88 (0.86–0.90)
OP drug use by ADRD, NH residents (subgroup)0.66 (0.64–0.69)

OP medication, nursing home (NH) residents (vs non-NH)

OR for OP medication in NH residents
0.61 (95% CI: 0.58-0.64)

Original publication

National trends in osteoporosis medication use among Medicare beneficiaries with and without Alzheimer’s disease/related dementias. Osteoporos Int. Published 2 February 2023. doi:10.1007/s00198-023-06680-3

Composed by AI from the published abstract and checked against it. How Briefs are made →

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