Pediatric rheumatology

Markerless gait analysis for children and adolescents with juvenile idiopathic arthritis using a machine learning pipeline

Pediatr Rheumatol Online JPublished Validation and cross-sectional comparative study

Authors' conclusion

The proposed single-camera, markerless pipeline can provide reliable and valid gait data using standard video equipment in children. Differences in gait patterns between JIA patients and TD peers were generally small, likely due to effective disease control.

Study context

Population
Children and adolescents with Juvenile Idiopathic Arthritis (JIA) and typically developing peers, age 1.8–17.4 years12 in validation subset
Participants
108 children
Comparison
JIA with lower-extremity involvement vs typically developing peers; markerless vs marker-based gait analysis
  • JIAn = 60
  • Typically developing (TD)n = 48reference
Outcome
Feasibility and validity of markerless gait analysis vs marker-based systems
Methodological detailsmarkerless single-camera gait analysis, machine learning pipeline, validation against marker-based motion capture, Statistical Parametric Mapping
  • Markerless single-camera gait analysis
  • Machine learning pipeline
  • Validation against marker-based motion capture
  • Statistical Parametric Mapping

Performance

As reported in the abstract

Agreement of markerless vs marker-based joint movement patterns
  • Robust agreement between joint movement patterns of the markerless and the marker-based approach

Further findings

OutcomeJIATD
Knee range of motion, JIA with active arthritis vs TD, across all age groupsJIA value refers to patients with active arthritis46.349.8

Joint angle trajectories between groups

Differences between groups remained limited overall

Original publication

Markerless gait analysis for children and adolescents with juvenile idiopathic arthritis using a machine learning pipeline. Pediatr Rheumatol Online J. Published 28 April 2026. doi:10.1186/s12969-026-01211-w

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