Vasculitis & polymyalgia rheumatica
Low incidence of late-onset giant cell arteritis during the first year in patients with polymyalgia rheumatica–a repeated imaging study
Authors' conclusion
This study is the first to demonstrate a low incidence rate of late-onset GCA in PMR patients within the first year, employing repeated imaging to exclude GCA at baseline and diagnose GCA during follow-up.
Study context
- Population
- Treatment-naïve patients with a new clinical diagnosis of polymyalgia rheumatica (PMR) and without giant cell arteritis (GCA) symptomsfinal PMR diagnosis
- Participants
- 62 patients
- Outcome
- Incidence of late-onset GCA in patients diagnosed with PMR
- Follow-up
- First year
Methodological detailsrepeated imaging (vascular US and FDG-PET/CT), rapid referral clinics
- Repeated imaging (vascular US and FDG-PET/CT)
- Rapid referral clinics
Main finding
As reported in the abstract
Late-onset GCA incidence · one-year follow-up
PMR
32 per 1000 person-years
2 of 62
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Baseline prevalence of subclinical GCA | PMR 3% |
- Baseline prevalence of subclinical GCA: 2 patients with concurrent subclinical GCA and PMR at baseline excluded
Original publication
Low incidence of late-onset giant cell arteritis during the first year in patients with polymyalgia rheumatica–a repeated imaging study. Rheumatology (Oxford). Published 24 August 2024. doi:10. 1093/ rheumatology/ keae463
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