Keep an Eye on the Back: Spondyloarthritis in Patients With Acute Anterior Uveitis
Authors' conclusion
Our study revealed a high prevalence of SpA in AAU patients overall, as well as a high prevalence of previously undiagnosed SpA in AAU patients.
Study context
- Population
- Prospectively recruited consecutive patients with noninfectious acute anterior uveitis (AAU)
- Participants
- 189 participants
- Exposure
- AAU patients with spondyloarthritis (SpA) vs AAU patients without SpA; Dublin Uveitis Evaluation Tool (DUET) vs ASAS referral tools
- Outcome
- Prevalence of SpA in patients with AAU
Methodological detailsconsecutive patients, structured rheumatologic assessment including MRI of the sacroiliac joints
- Consecutive patients
- Structured rheumatologic assessment including MRI of the sacroiliac joints
Main finding
As reported in the abstract
SpA prevalence in AAU
Diagnosed as having SpA
106
56%
Predominantly axial SpA among SpA patients
93%
Peripheral SpA
7
SpA diagnosed for the first time
74
70%
Observational data: associations, not effects.
Further findings
Performance of referral tools for SpA
Specificity
Sensitivity
- Performance of referral tools for SpA — SpA patients missed by both referral strategies
- more than 20%
Factors associated with SpA (multivariable logistic regression)
- Psoriasis, OR
- 12.5 (1.3-120.2) (95% CI)
- HLA-B27 positivity, OR
- 6.3 (2.4-16.4) (95% CI)
- Elevated CRP, OR
- 4.8 (1.9-12.4) (95% CI)
- Male sex, OR
- 2.1 (1.1-4.2) (95% CI)
- None of the ophthalmologic parameters were predictive of SpA
Original publication
Keep an Eye on the Back: Spondyloarthritis in Patients With Acute Anterior Uveitis. Arthritis Rheumatol. Published 23 December 2022. doi:10.
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