Integrating Patient Reported Outcomes Measurement Information System (PROMIS) Measures in a Treat-to-Target Approach to Standardize Patient-Centered Treatment of Rheumatoid Arthritis
Authors' conclusion
The integration of PROMIS measures into the T2T approach for RA care was associated with improvements in disease activity, and improvement in disease activity was associated with improvements in PROMIS measures.
Study context
- Population
- Patients with rheumatoid arthritis (RA) treated by rheumatologists using a patient-centered treat-to-target (T2T) approach integrating PROMIS measures (depression, fatigue, pain interference, physical function, social function); median age 57 years, 90.8% femaleanalytical sample
- Participants
- 119 patients
- Exposure
- Modified T2T approach integrating PROMIS measures; Clinical Disease Activity Index (CDAI) improved (>5 points) vs unchanged or worsened CDAI
- CDAI > 10n = 63
- CDAI ≤ 10n = 53
- Outcome
- Improvement in CDAI by > 5 points and change in PROMIS t scores; satisfaction with care
- Follow-up
- 1 year
Methodological detailslongitudinal, observational, pilot study
- Longitudinal
- Observational
- Pilot study
Main finding
As reported in the abstract
Improvement in CDAI by > 5 points
Observational data: associations, not effects.
Further findings
PROMIS domains
- Across all participants, CDAI improvement by > 5 points correlated with improvements in the 5 PROMIS domains
Satisfaction with RA treatment
- Satisfaction with RA treatment increased
Original publication
Integrating PROMIS Measures in a Treat-to-Target Approach to Standardize Patient-Centered Treatment of Rheumatoid Arthritis. J Rheumatol. Published 1 May 2023. doi:10.
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