Lupus & antiphospholipid syndrome
Increased healthcare utilisation in the 5 years preceding systemic lupus erythematosus diagnosis: a Danish nationwide cohort study
Authors' conclusion
Increased healthcare utilisation years before SLE diagnosis suggests that early symptoms are present and prompt medical attention long before formal diagnosis.
Study context
- Population
- Danish national healthcare registries, 2006–2021: individuals diagnosed with systemic lupus erythematosus (SLE) and matched healthy individuals (83.8% female; average age 47.1 years)matched cohort
- Participants
- 2,022 vs 20,019
- Exposure
- SLE vs matched reference individuals
- SLEn = 2,022
- Referencesn = 20,019reference
- Outcome
- Healthcare utilisation (GP visits, specialist consultations, prescriptions, blood tests, diagnostic imaging, hospital admissions) in the 5 years preceding SLE diagnosis
- Follow-up
- 5 years preceding diagnosis
Methodological detailsmatched, negative binomial regression adjusted for demographic and clinical covariates
- Matched
- Negative binomial regression adjusted for demographic and clinical covariates
Main finding
As reported in the abstract
GP contacts in the 5 years preceding SLE diagnosis · last 6 months before diagnosis
SLE
12
annual general practitioner (GP) contacts
References
4
contacts per year
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Increased healthcare utilisation in the 5 years preceding systemic lupus erythematosus diagnosis: a Danish nationwide cohort study. Ann Rheum Dis. Published 24 February 2025. doi:10.
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