Incidence of and Risk of Mortality After Hip Fractures in Rheumatoid Arthritis Relative to the General Population
Main finding · Hip fracturesResult — go to the resultIncidence rate ratio 1.28 95% CI 1.20–1.37Authors' conclusion
People with RA had a greater risk of hip fractures, but no greater risk of mortality post fracture, than the general population.
Study context
- Population
- Patients with incident rheumatoid arthritis (RA) diagnosed 1997–2009, followed until 2014, and matched general population controls, British Columbia
- Participants
- 37,616 vs 75,213
- Exposure
- RA vs age- and sex-matched general population controls
- RAn = 37,616
- Controlsn = 75,213reference
- Outcome
- Hip fracture incidence and risk; all-cause mortality after hip fracture
Methodological detailslongitudinal, incident cohort, age-matched and sex-matched general population controls, administrative health data, Cox proportional hazards models
- Longitudinal
- Incident cohort
- Age-matched and sex-matched general population controls
- Administrative health data
- Cox proportional hazards models
Main finding
Hip fractures
Incidence rate ratio
1.28
95% CI 1.20–1.37
Events by group
RA
1,314
events
Controls
2,083
events
RAvs Controls
IRR 1.28 (95% CI 1.20–1.37)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mean age at time of fracture
Postfracture all-cause mortality · 1 year and 5 years
- Postfracture mortality risk at one-year and five-years did not differ between RA and general population controls
Sensitivity analysis: RA patients who received DMARDs only
- Results were similar
Original publication
Incidence of and Risk of Mortality After Hip Fractures in Rheumatoid Arthritis Relative to the General Population. Arthritis Care Res (Hoboken). Published 22 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →